M.J. and T.F. are cofounders and have equity ownership in Cantargia AB (Ideon To study the expression of LSC markers in more detail, IL1RAP, CD25 and.

In the CANFOUR trial, treatment using Cantargia’s proprietary antibody CAN04, directed towards the molecular target IL1RAP, is investigated in patients with cancer. CAN04 works through a dual immuno-oncology mode of action and stimulates immune cells to eradicate tumor cells as well as counteracts tumor inflammation by blocking interleukin-1 signalling.

The basis for this is the protein IL1RAP that is involved in a number of diseases and where Cantargia has established a platform. 2021-03-19 · Cantargia AB today announced new preclinical results strengthening the development plan of the antibody CAN10 for treatment of myocarditis and systemic sclerosis. In preclinical studies of Om Cantargia Cantargia AB (publ), reg.no. 556791-6019, är ett bioteknikbolag som utvecklar antikroppsbaserade behandlingar för livshotande sjukdomar. Den ursprungliga upptäckten från forskargruppen bakom Cantargia var ett överuttryck av en specifik målmolekyl, interleukin 1 receptor accessory protein “IL1RAP”, i leukemistamceller.

Cantargia il1rap

PRESS RELEASE PR Newswire . Mar. 10, 2020, 08:58 AM. STOCKHOLM, March 10, 2020 /PRNewswire/ -- Cantargia AB … Cantargia 7 juli, 2020 Resultat i fas 2a närmar sig Kort om prekliniskt skede. Bolaget befinner sig i en fas 2a CAN04. Bolagets kunskapsbas forskning kring ett inflammatoriskt protein, IL1RAP, som återfinns på tumörceller stort antal cancersjukdomar IL1RAP ingår i den stora familjen av interleukin inflammatoris Cantargia har tidigare visat att antikroppar riktade mot IL1RAP kan blockera IL-1 signalering samt stimulera avdödning av tumörceller i olika prekliniska cancermodeller. De data som presenterades visar att IL1RAP uttrycks på flera cellinjer av trippelnegativ bröstcancer och icke-småcellig lungcancer. Cantargia's second project, currently in the research phase, is aimed at developing an IL1RAP-binding antibody that is optimised for treatment of autoimmune and inflammatory diseases.

Cantargia's vision is to develop and secure the new generation of targeted medicines against IL1RAP as an important part of tomorrow's more effective cancer treatments. The vision also includes developing new product candidates with the potential to treat even autoimmune / inflammatory diseases.

Pancreatic Ductal. 23 Aug 2019 IL1RAP was found in the tumor microenvironment in all samples and approximately 80 % of the patients contained IL1RAP positive cancer cells. Description. Cantargia AB is engaged in the development of products used in the treatment of cancer.

Cantargia is a clinical stage biotechnology company based in Sweden, established in 2009 and listed on Nasdaq Stockholm main market. It is developing two antibodies against IL1RAP, nidanilimab (CAN04) and CANxx. Nidanilimab is being studied in a Phase I/II CANFOUR in solid tumours focusing on NSCLC and pancreatic cancer.

Cantargia AB is engaged in the development of products used in the treatment of cancer. It has developed specific antibodies against IL1RAP to treat 28 Jan 2015 The IPO is intended to give Cantargia the cash to push ahead with lead candidate targets interleukin 1 receptor accessory protein (IL1RAP), 10 mars 2020 — Cantargia utvecklar antikropps-baserade läkemedel riktade mot interleukin 1 receptor accessory protein (IL1RAP). Det längst komna 16 apr. 2018 — Idag presenterar Cantargia AB nya data kring antikroppsterapi riktad mot Cantargias antikroppar mot IL1RAP kan blockera IL-1-systemet och 19 mars 2021 — Cantargia AB rapporterade idag om nya prekliniska resultat som stärker Antikroppen CAN10 binder IL1RAP med hög affinitet och fungerar 10 feb. 2021 — Cantargia utvecklar antikroppsbaserade läkemedel mot interleukin-1 receptor accessory protein (IL1RAP). Antikroppen CAN04 binder IL1RAP 10 mars 2020 — In addition, Cantargia also has patents on antibody therapy targeting IL1RAP in both solid tumors and in hematological cancer. Besides the 10 mars 2020 — Cantargia AB meddelade idag förvärvet av en patentportfölj från Cellerant Therapeutics Inc vilken täcker olika aspekter runt "interleukin 1 av H Ågerstam · 2015 · Citerat av 67 — The interleukin 1 receptor accessory protein (IL1RAP; IL1R3) is for fruitful discussions and Cantargia AB for contributing antibodies used in 10 feb.

Vidare spelar IL1RAP en central roll i Cantargia is developing antibodies against IL1RAP for treatment of life-threatening diseases.
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2019 — Cantargia meddelar nya positiva prekliniska data som innebär Målmolekylen för CAN04, IL1RAP, har påvisats på cancercellerna hos cirka 10 mars 2021 — Cantargia's lead asset CAN04 (anti-IL1RAP) is a potential competitor. While we acknowledge that Novartis's data has created negative Cantargias fortsatta forskning har visat att IL1RAP dessutom uttrycks i solida tumörer från flera olika cancerformer. Vidare spelar IL1RAP en central roll i Cantargia is developing antibodies against IL1RAP for treatment of life-threatening diseases. The company's main project, the immuno-oncology antibody 4 juli 2019 — Cantargia utvecklar antikroppsbaserade läkemedel mot interleukin 1 receptor accessory protein (IL1RAP).

With the CANxx platform, the goal is to build on the platform of novel IL1RAP-binding antibodies. Cantargia's vision is to develop and secure the new generation of targeted medicines against IL1RAP as an important part of tomorrow's more effective cancer treatments. The vision also includes developing new product candidates with the potential to treat even autoimmune / inflammatory diseases.
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8 Apr 2020 CAN04, an antibody targeting interleukin 1 receptor accessory protein (IL1RAP), is currently being investigated for treatment of non-small cell

While we acknowledge that Novartis's data has created negative Cantargias fortsatta forskning har visat att IL1RAP dessutom uttrycks i solida tumörer från flera olika cancerformer.

Cantargia acquires Cellerant IP on IL1RAP Tue, Mar 10, 2020 08:45 CET. Cantargia AB today announced the acquisition of a patent portfolio from Cellerant Therapeutics Inc covering aspects around the interleukin 1 receptor accessory protein (IL1RAP).

556791-6019, is a biotechnology company that develops antibody-based treatments for life-threatening diseases. The basis for this is the protein IL1RAP that is involved in a number of diseases and where Cantargia has established a platform. Cantargia AB meddelade idag förvärvet av en patentportfölj från Cellerant Therapeutics Inc vilken täcker olika aspekter runt ”interleukin 1 receptor accessory protein” (IL1RAP). Den förvärvade patentportföljen inkluderar ett amerikanskt patent kring IL1RAP som måltavla för antikroppsterapi inom leukemi.

2020-03-10 Cantargia erhåller patentgodkännande i Kina avseende antikroppsbehandling mot IL1RAP i solida tumörer fre, jan 05, 2018 08:30 CET. Cantargia AB (”Cantargia”) meddelar att det kinesiska patentverket State Intellectual Property Office (”SIPO”) har utfärdat ett formellt patentgodkännande avseende bolagets ansökan kring IL1RAP som målmolekyl för antikroppsterapi av flera typer av Om Cantargia Cantargia AB (publ), reg.no. 556791-6019, är ett bioteknikbolag som utvecklar antikroppsbaserade behandlingar för livshotande sjukdomar. Den ursprungliga upptäckten från forskargruppen bakom Cantargia var ett överuttryck av en specifik målmolekyl, interleukin 1 receptor accessory protein “IL1RAP”, i leukemistamceller.